PI4KB (NM_002651) Human Recombinant Protein

Product Specifications

Background

Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5, -trisphosphate (PIP) . May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human phosphatidylinositol 4-kinase, catalytic, beta (PI4KB)

Synonyms

NPIK; PI4K-BETA; PI4K92; PI4KBETA; PI4KIII; PI4KIIIBETA; PIK4CB

Gene ID

5298

UniProt

Q9UBF8, A0A0B4J1S8

Accession Number mRNA

NM_002651

Chromosomal Location

1q21.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system

Field of Research

Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

92.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.