HIP1R (NM_003959) Human Recombinant Protein
Product Specifications
Background
Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain) . May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human huntingtin interacting protein 1 related (HIP1R)
Synonyms
HIP3; HIP12; ILWEQ
Gene ID
9026
UniProt
O75146
Accession Number mRNA
NM_003959
Chromosomal Location
12q24.31
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
119.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HIP1R
Species
Human
Protein ID
NP_003950
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9026
Uniprot URL
https://www.uniprot.org/uniprot/O75146
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003959
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003950
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