H2BC9 (NM_003524) Human Recombinant Protein
Product Specifications
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
Overview
Recombinant protein of human histone cluster 1, H2bh (HIST1H2BH)
Synonyms
H2B/j; H2BFJ; HIST1H2BH
Gene ID
8345
UniProt
Q93079
Accession Number mRNA
NM_003524
Chromosomal Location
6p22.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Systemic lupus erythematosus
Field of Research
Systemic lupus erythematosus
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
13.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
H2BC9
Species
Human
Protein ID
NP_003515
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8345
Uniprot URL
https://www.uniprot.org/uniprot/Q93079
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003524
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003515
Frequently Asked Questions
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