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Annexin VI (ANXA6) (NM_004033) Human Recombinant Protein

Product Specifications

Background

Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010]

Overview

Recombinant protein of human annexin A6 (ANXA6), transcript variant 2

Synonyms

Annexin A6; annexin VI; annexin VI (p68) ; ANX6; calcium-binding protein p68; calelectrin; calphobindin II; CBP68

Gene ID

309

UniProt

P08133

Accession Number mRNA

NM_004033

Chromosomal Location

5q33.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

75.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ANXA6

Species

Human

Protein ID

NP_004024

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/309

Uniprot URL

https://www.uniprot.org/uniprot/P08133

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004033

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004024

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