Annexin VI (ANXA6) (NM_004033) Human Recombinant Protein
Product Specifications
Background
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010]
Synonyms
Annexin A6; annexin VI; annexin VI (p68) ; ANX6; calcium-binding protein p68; calelectrin; calphobindin II; CBP68
Gene ID
309
UniProt
P08133
Accession Number mRNA
NM_004033
Chromosomal Location
5q33.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
75.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ANXA6
Species
Human
Protein ID
NP_004024
Overview
Recombinant protein of human annexin A6 (ANXA6), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/309
Uniprot URL
https://www.uniprot.org/uniprot/P08133
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004033
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004024
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