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HAO1 (NM_017545) Human Recombinant Protein

Product Specifications

Background

This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human hydroxyacid oxidase (glycolate oxidase) 1 (HAO1)

Synonyms

GOX; GOX1; HAOX1

Gene ID

54363

UniProt

Q9UJM8, A8K058

Accession Number mRNA

NM_017545

Chromosomal Location

20p12.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Glyoxylate and dicarboxylate metabolism, Metabolic pathways

Field of Research

Glyoxylate and dicarboxylate metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

40.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

HAO1

Species

Human

Protein ID

NP_060015

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/54363

Uniprot URL

https://www.uniprot.org/uniprot/Q9UJM8

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_017545

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_060015

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