FAM83D (NM_030919) Human Recombinant Protein
Product Specifications
Background
Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition. Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC (PubMed:24344117) . May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade (PubMed:25646692) . May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22.[UniProtKB/Swiss-Prot Function]
Synonyms
C20orf129; CHICA; dJ616B8.3
Gene ID
81610
UniProt
Q9H4H8
Accession Number mRNA
NM_030919
Chromosomal Location
20q11.23
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
67.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FAM83D
Species
Human
Protein ID
NP_112181
Overview
Recombinant protein of human family with sequence similarity 83, member D (FAM83D)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/81610
Uniprot URL
https://www.uniprot.org/uniprot/Q9H4H8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_030919
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_112181
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