SKAP55 (SKAP1) (NM_003726) Human Recombinant Protein
Product Specifications
Background
This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008]
Synonyms
HEL-S-81p; SCAP1; SKAP55
Gene ID
8631
UniProt
Q86WV1
Accession Number mRNA
NM_003726
Chromosomal Location
17q21.32
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
41.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SKAP1
Species
Human
Protein ID
NP_003717
Overview
Recombinant protein of human src kinase associated phosphoprotein 1 (SKAP1), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8631
Uniprot URL
https://www.uniprot.org/uniprot/Q86WV1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003726
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003717
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