DYNC1I1 (NM_004411) Human Recombinant Protein
Selected Variant
PH35512M5
Size: 20 µg
Product Specifications
Background
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human dynein, cytoplasmic 1, intermediate chain 1 (DYNC1I1), transcript variant 1
Synonyms
DNCI1; DNCIC1
Gene ID
1780
UniProt
O14576, A4D1I7, Q8N542
Accession Number mRNA
NM_004411
Chromosomal Location
7q21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
72.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DYNC1I1
Species
Human
Protein ID
NP_004402
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1780
Uniprot URL
https://www.uniprot.org/uniprot/O14576
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004411
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004402
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog