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RAP1GAP2 (NM_015085) Human Recombinant Protein

Product Specifications

Background

This gene encodes a GTPase-activating protein that activates the small guanine-nucleotide-binding protein Rap1 in platelets. The protein interacts with synaptotagmin-like protein 1 and Rab27 and regulates secretion of dense granules from platelets at sites of endothelial damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Overview

Recombinant protein of human GTPase activating Rap/RanGAP domain-like 4 (GARNL4), transcript variant 1

Synonyms

GARNL4; RAP1GA3

Gene ID

23108

UniProt

Q684P5

Accession Number mRNA

NM_015085

Chromosomal Location

17p13.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

79.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

RAP1GAP2

Species

Human

Protein ID

NP_055900

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/23108

Uniprot URL

https://www.uniprot.org/uniprot/Q684P5

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_015085

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_055900

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