DCTD (NM_001921) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human dCMP deaminase (DCTD), transcript variant 2
Synonyms
MGC111062
Gene ID
1635
UniProt
P32321
Accession Number mRNA
NM_001921
Chromosomal Location
4q35.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolic pathways, Pyrimidine metabolism
Field of Research
Metabolic pathways, Pyrimidine metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
19.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DCTD
Species
Human
Protein ID
NP_001912
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1635
Uniprot URL
https://www.uniprot.org/uniprot/P32321
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001921
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001912
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