HMGA1 (NM_145904) Human Recombinant Protein
Product Specifications
Background
This gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes. [provided by RefSeq, Jan 2016]
Synonyms
AL023995; high mobility group AT-hook 1; high mobility group protein I; HMG-I (Y) ; HMG-R, HMGIY, HMGA1A, MGC4242, MGC4854, MGC12816; Hmga1a; Hmga1b; Hmgi; HMGI (Y) ; Hmgiy; HMGY; MGC102580
Gene ID
3159
UniProt
P17096
Accession Number mRNA
NM_145904
Chromosomal Location
6p21.31
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Stem cell - Pluripotency, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors
Molecular Weight
11.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HMGA1
Species
Human
Protein ID
NP_665911
Overview
Recombinant protein of human high mobility group AT-hook 1 (HMGA1), transcript variant 6
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3159
Uniprot URL
https://www.uniprot.org/uniprot/P17096
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_145904
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_665911
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