CARD14 (NM_024110) Human Recombinant Protein
Product Specifications
Background
This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]
Synonyms
BIMP2; CARMA2; PRP; PSORS2; PSS1
Gene ID
79092
UniProt
Q9BXL6
Accession Number mRNA
NM_024110
Chromosomal Location
17q25.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
113.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CARD14
Species
Human
Protein ID
NP_077015
Overview
Recombinant protein of human caspase recruitment domain family, member 14 (CARD14), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/79092
Uniprot URL
https://www.uniprot.org/uniprot/Q9BXL6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024110
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_077015
Curated Selection
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