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Kallikrein 5 (KLK5) (NM_001077491) Human Recombinant Protein

Product Specifications

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human kallikrein-related peptidase 5 (KLK5), transcript variant 2

Synonyms

KLK-L2; KLKL2; SCTE

Gene ID

25818

UniProt

Q9Y337

Accession Number mRNA

NM_001077491

Chromosomal Location

19q13.41

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protease, Secreted Protein, Transmembrane

Molecular Weight

28.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

KLK5

Species

Human

Protein ID

NP_001070959

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/25818

Uniprot URL

https://www.uniprot.org/uniprot/Q9Y337

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001077491

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001070959

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