Kallikrein 5 (KLK5) (NM_001077491) Human Recombinant Protein
Product Specifications
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Synonyms
KLK-L2; KLKL2; SCTE
Gene ID
25818
UniProt
Q9Y337
Accession Number mRNA
NM_001077491
Chromosomal Location
19q13.41
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protease, Secreted Protein, Transmembrane
Molecular Weight
28.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KLK5
Species
Human
Protein ID
NP_001070959
Overview
Recombinant protein of human kallikrein-related peptidase 5 (KLK5), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/25818
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y337
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001077491
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001070959
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