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TAPA1 (CD81) (NM_004356) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Overview

Recombinant protein of human CD81 molecule (CD81)

Synonyms

CVID6; S5.7; TAPA1; TSPAN28

Gene ID

975

UniProt

P60033, A0A024RCB7

Accession Number mRNA

NM_004356

Chromosomal Location

11p15.5

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

B cell receptor signaling pathway

Field of Research

B cell receptor signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Activity

27408937275119442760143728105773

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

Molecular Weight

25.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CD81

Species

Human

Protein ID

NP_004347

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/975

Uniprot URL

https://www.uniprot.org/uniprot/P60033

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004356

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004347

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