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NDST3 (NM_004784) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that define the specific ligand binding activities of heparan sulfate and heparin. [provided by RefSeq, Nov 2008]

Overview

Recombinant protein of human N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 (NDST3)

Synonyms

HSST3

Gene ID

9348

UniProt

O95803

Accession Number mRNA

NM_004784

Chromosomal Location

4q26

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Heparan sulfate biosynthesis, Metabolic pathways

Field of Research

Heparan sulfate biosynthesis, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

100.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

NDST3

Species

Human

Protein ID

NP_004775

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9348

Uniprot URL

https://www.uniprot.org/uniprot/O95803

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004784

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004775

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