NDST3 (NM_004784) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that define the specific ligand binding activities of heparan sulfate and heparin. [provided by RefSeq, Nov 2008]
Overview
Recombinant protein of human N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 (NDST3)
Synonyms
HSST3
Gene ID
9348
UniProt
O95803
Accession Number mRNA
NM_004784
Chromosomal Location
4q26
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Heparan sulfate biosynthesis, Metabolic pathways
Field of Research
Heparan sulfate biosynthesis, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
100.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NDST3
Species
Human
Protein ID
NP_004775
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9348
Uniprot URL
https://www.uniprot.org/uniprot/O95803
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004784
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004775
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