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Glutamyl Prolyl tRNA synthetase (EPRS) (NM_004446) Human Recombinant Protein

Product Specifications

Background

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human glutamyl-prolyl-tRNA synthetase (EPRS)

Synonyms

EARS; EPRS; GLUPRORS; HLD15; PARS; PIG32; QARS; QPRS

Gene ID

2058

UniProt

P07814

Accession Number mRNA

NM_004446

Chromosomal Location

1q41

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Aminoacyl-tRNA biosynthesis, Metabolic pathways, Porphyrin and chlorophyll metabolism

Field of Research

Aminoacyl-tRNA biosynthesis, Metabolic pathways, Porphyrin and chlorophyll metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Activity

25759500

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

170.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EPRS

Species

Human

Protein ID

NP_004437

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2058

Uniprot URL

https://www.uniprot.org/uniprot/P07814

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004446

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004437

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