GPLD1 (NM_001503) Human Recombinant Protein

Product Specifications

Background

Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human glycosylphosphatidylinositol specific phospholipase D1 (GPLD1), transcript variant 1

Synonyms

GPIPLD; GPIPLDM; PIGPLD; PIGPLD1; PLD

Gene ID

2822

UniProt

P80108

Accession Number mRNA

NM_001503

Chromosomal Location

6p22.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Glycosylphosphatidylinositol (GPI) -anchor biosynthesis

Field of Research

Glycosylphosphatidylinositol (GPI) -anchor biosynthesis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Secreted Protein

Molecular Weight

89.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.