AMSH (STAMBP) (NM_213622) Human Recombinant Protein
Product Specifications
Background
Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
AMSH; MICCAP
Gene ID
10617
UniProt
O95630, A0A140VK54
Accession Number mRNA
NM_213622
Chromosomal Location
2p13.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Endocytosis
Field of Research
Endocytosis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
47.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
STAMBP
Species
Human
Protein ID
NP_998787
Overview
Recombinant protein of human STAM binding protein (STAMBP), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10617
Uniprot URL
https://www.uniprot.org/uniprot/O95630
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_213622
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_998787
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