IRF8 (NM_002163) Human Recombinant Protein
Product Specifications
Background
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human interferon regulatory factor 8 (IRF8)
Synonyms
H-ICSBP; ICSBP; ICSBP1; IMD32A; IMD32B; IRF-8
Gene ID
3394
UniProt
Q02556
Accession Number mRNA
NM_002163
Chromosomal Location
16q24.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
48.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
IRF8
Species
Human
Protein ID
NP_002154
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3394
Uniprot URL
https://www.uniprot.org/uniprot/Q02556
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002163
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002154
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