SIAT4A (ST3GAL1) (NM_003033) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008]
Synonyms
1; Gal-NAc6S; SIAT4A; SIATFL; ST3GalA; ST3GalA.1; ST3GalIA; ST3O
Gene ID
6482
UniProt
Q11201, A0A024R9L6
Accession Number mRNA
NM_003033
Chromosomal Location
8q24.22
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Glycosphingolipid biosynthesis - ganglio series, Glycosphingolipid biosynthesis - globo series, Keratan sulfate biosynthesis, Metabolic pathways, O-Glycan biosynthesis
Field of Research
Glycosphingolipid biosynthesis - ganglio series, Glycosphingolipid biosynthesis - globo series, Keratan sulfate biosynthesis, Metabolic pathways, O-Glycan biosynthesis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein, Transmembrane
Molecular Weight
38.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ST3GAL1
Species
Human
Protein ID
NP_003024
Overview
Recombinant protein of human ST3 beta-galactoside alpha-2, 3-sialyltransferase 1 (ST3GAL1), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6482
Uniprot URL
https://www.uniprot.org/uniprot/Q11201
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003033
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003024
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