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SIAT4A (ST3GAL1) (NM_003033) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human ST3 beta-galactoside alpha-2, 3-sialyltransferase 1 (ST3GAL1), transcript variant 1

Synonyms

1; Gal-NAc6S; SIAT4A; SIATFL; ST3GalA; ST3GalA.1; ST3GalIA; ST3O

Gene ID

6482

UniProt

Q11201, A0A024R9L6

Accession Number mRNA

NM_003033

Chromosomal Location

8q24.22

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Glycosphingolipid biosynthesis - ganglio series, Glycosphingolipid biosynthesis - globo series, Keratan sulfate biosynthesis, Metabolic pathways, O-Glycan biosynthesis

Field of Research

Glycosphingolipid biosynthesis - ganglio series, Glycosphingolipid biosynthesis - globo series, Keratan sulfate biosynthesis, Metabolic pathways, O-Glycan biosynthesis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein, Transmembrane

Molecular Weight

38.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ST3GAL1

Species

Human

Protein ID

NP_003024

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6482

Uniprot URL

https://www.uniprot.org/uniprot/Q11201

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003033

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003024

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