What is the catalog number for MYBPC3 (NM_000256) Human Recombinant Protein?

The catalog number for MYBPC3 (NM_000256) Human Recombinant Protein is PH35363M5.

What sizes are available for MYBPC3 (NM_000256) Human Recombinant Protein?

MYBPC3 (NM_000256) Human Recombinant Protein is available in the following size(s): 20 µg.

Is MYBPC3 (NM_000256) Human Recombinant Protein in stock?

MYBPC3 (NM_000256) Human Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

MYBPC3 (NM_000256) Human Recombinant Protein

Product Specifications

Background

MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Homo sapiens myosin binding protein C, cardiac (MYBPC3)

Synonyms

CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C

Gene ID

4607

UniProt

Q14896, A5YM48

Accession Number mRNA

NM_000256

Chromosomal Location

11p11.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Field of Research

Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

140.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.