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NRF1 (NM_001040110) Human Recombinant Protein

Selected Variant

PH35329M5

Size: 20 µg

Product Specifications

Background

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2) -like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014]

Overview

Recombinant protein of human nuclear respiratory factor 1 (NRF1), transcript variant 2

Synonyms

ALPHA-PAL

Gene ID

4899

UniProt

Q16656, A0A024R770

Accession Number mRNA

NM_001040110

Chromosomal Location

7q32.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Huntington's disease

Field of Research

Huntington's disease

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transcription Factors

Molecular Weight

53.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

NRF1

Species

Human

Protein ID

NP_001035199

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/4899

Uniprot URL

https://www.uniprot.org/uniprot/Q16656

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001040110

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001035199

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