NRF1 (NM_001040110) Human Recombinant Protein
Selected Variant
PH35329M5
Size: 20 µg
Product Specifications
Background
This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2) -like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014]
Overview
Recombinant protein of human nuclear respiratory factor 1 (NRF1), transcript variant 2
Synonyms
ALPHA-PAL
Gene ID
4899
UniProt
Q16656, A0A024R770
Accession Number mRNA
NM_001040110
Chromosomal Location
7q32.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Huntington's disease
Field of Research
Huntington's disease
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
53.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NRF1
Species
Human
Protein ID
NP_001035199
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4899
Uniprot URL
https://www.uniprot.org/uniprot/Q16656
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001040110
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001035199
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog