UBE2I (NM_003345) Human Recombinant Protein
Product Specifications
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) (UBE2I), transcript variant 1
Synonyms
C358B7.1; P18; UBC9
Gene ID
7329
UniProt
P63279, A8K503
Accession Number mRNA
NM_003345
Chromosomal Location
16p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Ubiquitin mediated proteolysis
Field of Research
Ubiquitin mediated proteolysis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
17.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UBE2I
Species
Human
Protein ID
NP_003336
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7329
Uniprot URL
https://www.uniprot.org/uniprot/P63279
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003345
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003336
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