Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

JAK3 (NM_000215) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) . [provided by RefSeq, Jul 2008]

Synonyms

JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK

Gene ID

3718

UniProt

P52333, A0A024R7M7

Accession Number mRNA

NM_000215

Chromosomal Location

19p13.11

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Chemokine signaling pathway, Jak-STAT signaling pathway, Primary immunodeficiency

Field of Research

Chemokine signaling pathway, Jak-STAT signaling pathway, Primary immunodeficiency

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase

Molecular Weight

124.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

JAK3

Species

Human

Protein ID

NP_000206

Overview

Recombinant protein of human Janus kinase 3 (a protein tyrosine kinase, leukocyte) (JAK3)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3718

Uniprot URL

https://www.uniprot.org/uniprot/P52333

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000215

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000206

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

1-(2-Chloro-4-(4-chlorophenoxy)phenyl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-ol
TRC-C429253-10MG 10 mg

1-(2-Chloro-4-(4-chlorophenoxy)phenyl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-ol

Ask
View Details
Arylamine N-Acetyltransferase 1 (NAT1) Antibody
abx302364-01 20 µg

Arylamine N-Acetyltransferase 1 (NAT1) Antibody

Ask
View Details
Arylamine N-Acetyltransferase 1 (NAT1) Antibody
abx302364-02 50 µg

Arylamine N-Acetyltransferase 1 (NAT1) Antibody

Ask
View Details
Arylamine N-Acetyltransferase 1 (NAT1) Antibody
abx302364-03 100 µg

Arylamine N-Acetyltransferase 1 (NAT1) Antibody

Ask
View Details
Arylamine N-Acetyltransferase 1 (NAT1) Antibody
abx302364-04 200 µg

Arylamine N-Acetyltransferase 1 (NAT1) Antibody

Ask
View Details
Arylamine N-Acetyltransferase 1 (NAT1) Antibody
abx302364-05 1 mg

Arylamine N-Acetyltransferase 1 (NAT1) Antibody

Ask
View Details