C14orf130 (UBR7) (NM_175748) Human Recombinant Protein
Product Specifications
Background
This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome. [provided by RefSeq, Jul 2016]
Overview
Recombinant protein of human ubiquitin protein ligase E3 component n-recognin 7 (putative) (UBR7), transcript variant 2
Synonyms
C14orf130; LICAS
Gene ID
55148
UniProt
Q8N806
Accession Number mRNA
NM_175748
Chromosomal Location
14q32.12
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
47.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UBR7
Species
Human
Protein ID
NP_786924
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55148
Uniprot URL
https://www.uniprot.org/uniprot/Q8N806
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_175748
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_786924
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