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DMC1 (NM_007068) Human Recombinant Protein

Selected Variant

PH35219M5

Size: 20 µg

Product Specifications

Background

This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins) . Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Overview

Recombinant protein of human DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) (DMC1)

Synonyms

DJ199H16.1; DMC1H; LIM15

Gene ID

11144

UniProt

Q14565

Accession Number mRNA

NM_007068

Chromosomal Location

22q13.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

37.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

DMC1

Species

Human

Protein ID

NP_008999

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/11144

Uniprot URL

https://www.uniprot.org/uniprot/Q14565

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_007068

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_008999

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