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SCYL1 (NM_001048218) Human Recombinant Protein

Product Specifications

Background

This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human SCY1-like 1 (S. cerevisiae) (SCYL1), transcript variant B

Synonyms

GKLP; HT019; NKTL; NTKL; P105; SCAR21; TAPK; TEIF; TRAP

Gene ID

57410

UniProt

Q96KG9

Accession Number mRNA

NM_001048218

Chromosomal Location

11q13.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase

Molecular Weight

87.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SCYL1

Species

Human

Protein ID

NP_001041683

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/57410

Uniprot URL

https://www.uniprot.org/uniprot/Q96KG9

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001048218

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001041683

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