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TNFAIP8L3 (NM_207381) Human Recombinant Protein

Product Specifications

Background

Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human tumor necrosis factor, alpha-induced protein 8-like 3 (TNFAIP8L3)

Synonyms

TIPE3

Gene ID

388121

UniProt

Q5GJ75

Accession Number mRNA

NM_207381

Chromosomal Location

15q21.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

32.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

TNFAIP8L3

Species

Human

Protein ID

NP_997264

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/388121

Uniprot URL

https://www.uniprot.org/uniprot/Q5GJ75

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_207381

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_997264

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