ENTPD8 (NM_001033113) Human Recombinant Protein

Product Specifications

Background

Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human ectonucleoside triphosphate diphosphohydrolase 8 (ENTPD8), transcript variant 1

Synonyms

E-NTPDase; GLSR2492; NTPDase-8; UNQ2492

Gene ID

377841

UniProt

Q5MY95

Accession Number mRNA

NM_001033113

Chromosomal Location

9q34.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Purine metabolism, Pyrimidine metabolism

Field of Research

Purine metabolism, Pyrimidine metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

53.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.