INMT (NM_006774) Human Recombinant Protein
Product Specifications
Background
N-methylation of endogenous and xenobiotic compounds is a major method by which they are degraded. This gene encodes an enzyme that N-methylates indoles such as tryptamine. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream MINDY4 (aka FAM188B) gene. In rodents and other mammals such as cetartiodactyla this gene is in the opposite orientation compared to its orientation in human and other primates and this gene appears to have been lost in carnivora and chiroptera. [provided by RefSeq, Jul 2019]
Synonyms
TEMT
Gene ID
11185
UniProt
O95050
Accession Number mRNA
NM_006774
Chromosomal Location
7p14.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Tryptophan metabolism
Field of Research
Tryptophan metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
28.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
INMT
Species
Human
Protein ID
NP_006765
Overview
Recombinant protein of human indolethylamine N-methyltransferase (INMT)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11185
Uniprot URL
https://www.uniprot.org/uniprot/O95050
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006774
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006765
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