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MRAP (NM_206898) Human Recombinant Protein

Product Specifications

Background

This gene encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2. Alternatively spliced transcript variants have been described. [provided by RefSeq, Dec 2009]

Overview

Purified recombinant protein of Homo sapiens melanocortin 2 receptor accessory protein (MRAP), transcript variant 2

Synonyms

B27; C21orf61; FALP; FGD2; GCCD2

Gene ID

56246

UniProt

Q8TCY5

Accession Number mRNA

NM_206898

Chromosomal Location

21q22.11

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

11.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MRAP

Species

Human

Protein ID

NP_996781

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/56246

Uniprot URL

https://www.uniprot.org/uniprot/Q8TCY5

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_206898

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_996781

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