UROC1 (NM_144639) Human Recombinant Protein
Selected Variant
PH35117M5
Size: 20 µg
Product Specifications
Background
This gene encodes an enzyme involved in the second step of histidine catabolism, metabolizing urocanic acid to formiminoglutamic acid. Deficiency of this enzyme results in urocanic aciduria, and is an apparent cause of mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2021]
Overview
Recombinant protein of human urocanase domain containing 1 (UROC1)
Synonyms
HMFN0320; UROCD
Gene ID
131669
UniProt
Q96N76
Accession Number mRNA
NM_144639
Chromosomal Location
3q21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Histidine metabolism, Metabolic pathways
Field of Research
Histidine metabolism, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
74.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UROC1
Species
Human
Protein ID
NP_653240
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/131669
Uniprot URL
https://www.uniprot.org/uniprot/Q96N76
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_144639
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_653240
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