ARHGEF7 (NM_145735) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Mar 2016]
Synonyms
BETA-PIX; COOL-1; COOL1; Nbla10314; P50; P50BP; P85; P85COOL1; P85SPR; PAK3; PIXB
Gene ID
8874
UniProt
Q14155, Q5W9H1
Accession Number mRNA
NM_145735
Chromosomal Location
13q34
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Regulation of actin cytoskeleton
Field of Research
Regulation of actin cytoskeleton
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
87.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ARHGEF7
Species
Human
Protein ID
NP_663788
Overview
Recombinant protein of human Rho guanine nucleotide exchange factor (GEF) 7 (ARHGEF7), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8874
Uniprot URL
https://www.uniprot.org/uniprot/Q14155
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_145735
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_663788
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