BICD1 (NM_001714) Human Recombinant Protein
Product Specifications
Background
This gene encodes an adaptor protein that belongs to the bicaudal D family of dynein cargo adaptors. The encoded protein acts as an intracellular cargo transport cofactor that regulates the microtubule-based loading of cargo onto the dynein motor complex. It also controls dynein motor activity and coordination. It has a domain architecture consisting of coiled-coil domains at the N- and C-termini that are highly conserved in other family members. Naturally occurring mutations in this gene are associated with short telomere length and emphysema. [provided by RefSeq, Aug 2017]
Synonyms
Bic-D 1; BICD
Gene ID
636
UniProt
Q96G01
Accession Number mRNA
NM_001714
Chromosomal Location
12p11.21
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
110.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
BICD1
Species
Human
Protein ID
NP_001705
Overview
Recombinant protein of human bicaudal D homolog 1 (Drosophila) (BICD1), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/636
Uniprot URL
https://www.uniprot.org/uniprot/Q96G01
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001714
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001705
Curated Selection
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