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BICD1 (NM_001714) Human Recombinant Protein

Product Specifications

Background

This gene encodes an adaptor protein that belongs to the bicaudal D family of dynein cargo adaptors. The encoded protein acts as an intracellular cargo transport cofactor that regulates the microtubule-based loading of cargo onto the dynein motor complex. It also controls dynein motor activity and coordination. It has a domain architecture consisting of coiled-coil domains at the N- and C-termini that are highly conserved in other family members. Naturally occurring mutations in this gene are associated with short telomere length and emphysema. [provided by RefSeq, Aug 2017]

Overview

Recombinant protein of human bicaudal D homolog 1 (Drosophila) (BICD1), transcript variant 1

Synonyms

Bic-D 1; BICD

Gene ID

636

UniProt

Q96G01

Accession Number mRNA

NM_001714

Chromosomal Location

12p11.21

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

110.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

BICD1

Species

Human

Protein ID

NP_001705

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/636

Uniprot URL

https://www.uniprot.org/uniprot/Q96G01

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001714

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001705

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