GTF2IRD1 (NM_005685) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
Synonyms
BEN; CREAM1; GTF3; hMusTRD1alpha1; MUSTRD1; RBAP2; WBS; WBSCR11; WBSCR12
Gene ID
9569
UniProt
Q9UHL9
Accession Number mRNA
NM_005685
Chromosomal Location
7q11.23
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Basal transcription factors
Field of Research
Basal transcription factors
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
104.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GTF2IRD1
Species
Human
Protein ID
NP_005676
Overview
Recombinant protein of human GTF2I repeat domain containing 1 (GTF2IRD1), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9569
Uniprot URL
https://www.uniprot.org/uniprot/Q9UHL9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005685
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005676
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