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Syntenin 2 (SDCBP2) (NM_015685) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The encoded protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Read-through transcription also exists between this gene and the upstream FKBP1A (FK506 binding protein 1A, 12kDa) gene, as represented in GeneID:100528031. [provided by RefSeq, Sep 2011]

Synonyms

SITAC; SITAC18; ST-2; ST2

Gene ID

27111

UniProt

Q9H190

Accession Number mRNA

NM_015685

Chromosomal Location

20p13

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

22.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SDCBP2

Species

Human

Protein ID

NP_056500

Overview

Recombinant protein of human syndecan binding protein (syntenin) 2 (SDCBP2), transcript variant 2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/27111

Uniprot URL

https://www.uniprot.org/uniprot/Q9H190

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_015685

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_056500

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