HERC6 (NM_017912) Human Recombinant Protein
Selected Variant
PH35073M5
Size: 20 µg
Product Specifications
Background
HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710) -like domain (RLD) . The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]) .[supplied by OMIM, Mar 2008]
Overview
Recombinant protein of human hect domain and RLD 6 (HERC6)
Synonyms
FLJ20637
Gene ID
55008
UniProt
Q8IVU3
Accession Number mRNA
NM_017912
Chromosomal Location
4q22.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
114.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HERC6
Species
Human
Protein ID
NP_060382
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55008
Uniprot URL
https://www.uniprot.org/uniprot/Q8IVU3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_017912
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060382
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