C1S (NM_001734) Human Recombinant Protein
Product Specifications
Background
This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]
Synonyms
EDSPD2
Gene ID
716
UniProt
P09871
Accession Number mRNA
NM_001734
Chromosomal Location
12p13.31
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Complement and coagulation cascades, Systemic lupus erythematosus
Field of Research
Complement and coagulation cascades, Systemic lupus erythematosus
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protease
Molecular Weight
74.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
C1S
Species
Human
Protein ID
NP_001725
Overview
Recombinant protein of human complement component 1, s subcomponent (C1S), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/716
Uniprot URL
https://www.uniprot.org/uniprot/P09871
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001734
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001725
Curated Selection
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