C1S (NM_001734) Human Recombinant Protein

Product Specifications

Background

This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]

Overview

Recombinant protein of human complement component 1, s subcomponent (C1S), transcript variant 2

Synonyms

EDSPD2

Gene ID

716

UniProt

P09871

Accession Number mRNA

NM_001734

Chromosomal Location

12p13.31

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Complement and coagulation cascades, Systemic lupus erythematosus

Field of Research

Complement and coagulation cascades, Systemic lupus erythematosus

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protease

Molecular Weight

74.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.