GAB1 (NM_002039) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Overview

Recombinant protein of human GRB2-associated binding protein 1 (GAB1), transcript variant 2

Synonyms

GRB2-associated binding protein 1

Gene ID

2549

UniProt

Q13480, Q9HA84

Accession Number mRNA

NM_002039

Chromosomal Location

4q31.21

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

ErbB signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

Field of Research

ErbB signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

76.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.