Clathrin light chain (CLTA) (NM_007096) Human Recombinant Protein
Product Specifications
Background
Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 8 and 12. [provided by RefSeq, May 2010]
Synonyms
LCA
Gene ID
1211
UniProt
P09496
Accession Number mRNA
NM_007096
Chromosomal Location
9p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Endocytosis, Huntington's disease, Lysosome
Field of Research
Endocytosis, Huntington's disease, Lysosome
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
26.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CLTA
Species
Human
Protein ID
NP_009027
Overview
Recombinant protein of human clathrin, light chain (Lca) (CLTA), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1211
Uniprot URL
https://www.uniprot.org/uniprot/P09496
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007096
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_009027
Curated Selection
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