JIP2 (MAPK8IP2) (NM_016431) Human Recombinant Protein

Product Specifications

Background

This gene encodes a scaffold protein that is thought to be involved in the regulation of the c-Jun amino-terminal kinase signaling pathway. This protein has been shown to interact with and regulate the activity of MAPK8/JNK1 and MAP2K7/MKK7 kinases. [provided by RefSeq, Jun 2017]

Overview

Recombinant protein of human mitogen-activated protein kinase 8 interacting protein 2 (MAPK8IP2), transcript variant 2

Synonyms

IB2; JIP2; PRKM8IPL

Gene ID

23542

UniProt

Q13387

Accession Number mRNA

NM_016431

Chromosomal Location

22q13.33

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

MAPK signaling pathway

Field of Research

MAPK signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

84.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.