EHMT2/G9A (EHMT2) (NM_025256) Human Recombinant Protein
Product Specifications
Background
This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Synonyms
BAT8; C6orf30; G9A; GAT8; KMT1C; NG36
Gene ID
10919
UniProt
Q96KQ7
Accession Number mRNA
NM_025256
Chromosomal Location
6p21.33
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Lysine degradation
Field of Research
Lysine degradation
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
128.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EHMT2
Species
Human
Protein ID
NP_079532
Overview
Recombinant protein of human euchromatic histone-lysine N-methyltransferase 2 (EHMT2), transcript variant NG36/G9a-SPI
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10919
Uniprot URL
https://www.uniprot.org/uniprot/Q96KQ7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025256
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_079532
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