EHMT2/G9A (EHMT2) (NM_025256) Human Recombinant Protein

Product Specifications

Background

This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Overview

Recombinant protein of human euchromatic histone-lysine N-methyltransferase 2 (EHMT2), transcript variant NG36/G9a-SPI

Synonyms

BAT8; C6orf30; G9A; GAT8; KMT1C; NG36

Gene ID

10919

UniProt

Q96KQ7

Accession Number mRNA

NM_025256

Chromosomal Location

6p21.33

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Lysine degradation

Field of Research

Lysine degradation

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

128.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.