TRAF5 (NM_004619) Human Recombinant Protein

Product Specifications

Background

The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

Overview

Recombinant protein of human TNF receptor-associated factor 5 (TRAF5), transcript variant 1

Synonyms

MGC:39780; RNF84

Gene ID

7188

UniProt

O00463

Accession Number mRNA

NM_004619

Chromosomal Location

1q32.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Pathways in cancer, Small cell lung cancer

Field of Research

Pathways in cancer, Small cell lung cancer

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

64.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.