TRAF5 (NM_004619) Human Recombinant Protein
Product Specifications
Background
The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Synonyms
MGC:39780; RNF84
Gene ID
7188
UniProt
O00463
Accession Number mRNA
NM_004619
Chromosomal Location
1q32.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Pathways in cancer, Small cell lung cancer
Field of Research
Pathways in cancer, Small cell lung cancer
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
64.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TRAF5
Species
Human
Protein ID
NP_004610
Overview
Recombinant protein of human TNF receptor-associated factor 5 (TRAF5), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7188
Uniprot URL
https://www.uniprot.org/uniprot/O00463
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004619
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004610
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items