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Macrophage inflammatory protein 5 (CCL15) (NM_004167) Human Recombinant Protein

Product Specifications

Background

This gene is located in a cluster of similar genes in the same region of chromosome 17. These genes encode CC cytokines, which are secreted proteins characterized by two adjacent cysteines. The product of this gene is chemotactic for T cells and monocytes, and acts through C-C chemokine receptor type 1 (CCR1) . The proprotein is further processed into numerous smaller functional peptides. Naturally-occurring readthrough transcripts occur from this gene into the downstream gene, CCL14 (chemokine (C-C motif) ligand 14) . [provided by RefSeq, Jan 2013]

Overview

Recombinant protein of human chemokine (C-C motif) ligand 15 (CCL15), transcript variant 2

Synonyms

HCC-2; HMRP-2B; Lkn-1; LKN1; MIP-1d; MIP-5; NCC-3; NCC3; SCYA15; SCYL3; SY15

Gene ID

6359

UniProt

Q16663

Accession Number mRNA

NM_004167

Chromosomal Location

17q12

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Chemokine signaling pathway, Cytokine-cytokine receptor interaction

Field of Research

Chemokine signaling pathway, Cytokine-cytokine receptor interaction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Secreted Protein, Transmembrane

Molecular Weight

10.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CCL15

Species

Human

Protein ID

NP_004158

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6359

Uniprot URL

https://www.uniprot.org/uniprot/Q16663

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004167

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004158

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