AGXT2 (NM_031900) Human Recombinant Protein
Selected Variant
PH34950M5
Size: 20 µg
Product Specifications
Background
The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. It is an important regulator of methylarginines and is involved in the control of blood pressure in kidney. Polymorphisms in this gene affect methylarginine and beta-aminoisobutyrate metabolism, and are associated with carotid atherosclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Overview
Recombinant protein of human alanine-glyoxylate aminotransferase 2 (AGXT2), nuclear gene encoding mitochondrial protein
Synonyms
AGT2; BAIBA; DAIBAT
Gene ID
64902
UniProt
Q9BYV1
Accession Number mRNA
NM_031900
Chromosomal Location
5p13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Alanine, aspartate and glutamate metabolism
Field of Research
Alanine, aspartate and glutamate metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
52.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
AGXT2
Species
Human
Protein ID
NP_114106
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/64902
Uniprot URL
https://www.uniprot.org/uniprot/Q9BYV1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_031900
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_114106
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