FYN (NM_153047) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq, Jul 2008]
Synonyms
P59-FYN; SLK; SYN
Gene ID
2534
UniProt
P06241
Accession Number mRNA
NM_153047
Chromosomal Location
6q21
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Adherens junction, Axon guidance, Fc epsilon RI signaling pathway, Focal adhesion, Natural killer cell mediated cytotoxicity, Pathogenic Escherichia coli infection, Prion diseases, T cell receptor signaling pathway, Viral myocarditis
Field of Research
Adherens junction, Axon guidance, Fc epsilon RI signaling pathway, Focal adhesion, Natural killer cell mediated cytotoxicity, Pathogenic Escherichia coli infection, Prion diseases, T cell receptor signaling pathway, Viral myocarditis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
60 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FYN
Species
Human
Protein ID
NP_694592
Overview
Recombinant protein of human FYN oncogene related to SRC, FGR, YES (FYN), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2534
Uniprot URL
https://www.uniprot.org/uniprot/P06241
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_153047
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_694592
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