Laeverin (LVRN) (NM_173800) Human Recombinant Protein
Product Specifications
Background
Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo-maternal interface. On synthetic substrates it shows a marked preference for Leu-4-methylcoumaryl-7-amide (Leu-MCA) over Met-MCA, Arg-LCA and Lys-LCA. Cleaves the N-terminal amino acid of several peptides such as angiotensin-3, kisspeptin-10 and endokinin C.[UniProtKB/Swiss-Prot Function]
Synonyms
APQ; AQPEP; TAQPEP
Gene ID
206338
UniProt
Q6Q4G3, Q0P5U8
Accession Number mRNA
NM_173800
Chromosomal Location
5q23.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Protease, Transmembrane
Molecular Weight
113.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LVRN
Species
Human
Protein ID
NP_776161
Overview
Recombinant protein of human laeverin (LVRN)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/206338
Uniprot URL
https://www.uniprot.org/uniprot/Q6Q4G3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_173800
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_776161
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